At least 40 people have been killed and about 100 wounded after Syrian government forces fired missiles into a market near Damascus, according to a conflict monitor and a local rescue group.
The Syrian Observatory for Human Rights said government forces fired 12 missiles in Douma, 10 miles (15km) north-east of the capital.
Douma has suffered intense bombardment in recent months in a wave of strikes. The Syrian army has said the strikes have targeted insurgent groups that launched attacks on nearby government-held areas.
The Syrian Civil Defence group, which posted a picture on its Facebook page showing about a dozen bloodied bodies, said more than 45 people had died in the attack.
Many of Douma’s residents have fled the four-year-old conflict, moving to nearby rural areas. Medics say they have struggled to cope with large numbers of wounded in the intensified strikes.
A marathon day of peace talks are under way in Vienna, with Iran joining rivals Saudi Arabia and the US to try to orchestrate an end to the conflict in Syria.